Fluttershy and Nausicaa: Both are kind-hearted and gentle but can be genuinely terrifying if they’re pushed too far.
 
Rainbow Dash and San: Both are hot-headed and stubborn but can have a soft-side to them.
 
Rarity and Lady Eboshi: Sophisticated and intelligent but kind-hearted to those they care about.
 
Applejack and Lin: Rough at times but they stick close to those they care about.
 
Twilight Sparkle and Fio Piccolo: Both are skilled in their respective areas (Twilight in magic and Fio in planes).
 
Pinkie Pie and Ponyo: Energetic as hell.