[ORIGINAL DESCRIPTION]  
I’ve seen so many Overwatch/MLP crossovers, and yet all of them disappoint me. YOU HEAR THAT BRONIES? YOU DISAPPOINT ME! I AM DISAPPOINT!
 
But don’t worry, I forgive you.
 
Not really. Go to your room.
 
Anyway, I’m not super into this game, but I do know a few things so I decided to give my two cents on a good crossover idea, and here we go! Bare in mind I’m working on limited information.
 
Twilight Sparkle - Symmetra  
Both were child prodigies, both can be a bit obsessive compulsive, and both love order. Doesn’t hurt that Symmetra’s work often involves the creation of barriers, defensive strategy, and conjuring turrets. Symmetra also seems the most mage-like of the crew, so I decided this fit best for Twilight.
 
Rainbow Dash - Soldier 76  
I don’t know, something about the way Soldier 76 carries himself just seems to fit Dash. Very tough, brazen, and kind of mercenary.
 
Applejack - McCree  
I imagine you guys didn’t need me to make this connection. He’s basically a gunslinger cowboy from an old western film, so I felt ‘why not?’ Also considered Reinhardt, but decided against it.
 
Rarity - Widowmaker  
Graceful, precise, deadly, Widowmaker is almost like what you get when you combine the Sniper and the Spy from Team Fortress 2 into one character. She just has that air of deadliness fitting for her theme of spiders, and I felt that fit Rarity just right.
 
Pinkie Pie - D.Va  
Giant pink mech and the ability to make it explode? I don’t know, this just seemed right for Pinkie Pie for some reason, though I admit I say this partially out of a lack of a better idea.
 
Fluttershy - Bastion  
Bronies have told me I should focus more on Fluttershy’s kindness in the crossovers, and I decided this time I’ll give them what they want - Fluttershy as the single most peaceful character in Overwatch (incidentally, it isn’t the healer). Actually very proud of how Flutterbastion turned out!