Azalea and Berry Vine  
The biological parents of Anthea (Annie). Their whereabouts are unknow, their reason for leaving Anthea is unknown and whether they’re dead or alive is also unknown
 
Fluttershy  
Anthea’s adoptive mother. Fluttershy adopted Annie when she was around 4 or 5 years old from the Ponyville orphanage.
 
Button Mash and Sweetie Belle  
The parents of Pixel Bit. They live in Ponyville but travel a lot.
 
Rarity and Spike  
The parents of Crystal Clairty (Claire) and Turquoise Blitz (T). After they married, they lived in Canterlot until for Rarity’s job. They moved back to Ponyville when T was 5 years old.
 
Celestia and Discord  
The parents of Illusion.
 
Luna and Supernova  
The parents of Nidra. Supernova is one of. Luna’s nightguards.
 
Flash Sentry and Twilight Sparkle  
The parents of Starburst (Star) and Nightlight (Nighty). Over the years, things became very busy in Equestria and there were plenty threats along the way. As result, Twilight and Flash ended up spending a lot of time in Canterlot rather than in Ponyville.
 
Shining Armor and Cadence  
The parents of Valiant Heart (Val/Lance). They rule the Crystal Empire.
 
Pinkie Pie and Pokey Pierce  
The parents of Cotton Candy, Cloudy Skies (Sky) and Sugar Rush. They live in Ponyville.
 
Scootaloo and Rumble  
The parents of Echo. They live in Ponyville.
 
Thunderlane and Cloudchaser  
The parents of Whirlwind. They live in Cloudsdale.
 
Rainbow Dash and Soarin  
The parents of Prism Bolt (Priz) and Icy Storm. Rainbow used to live in Ponyville but moved to Cloudsdale with Soarin after marriage.
 
Cheerilee and Big Macintosh  
The parents of Red June. They live in Ponyville but not Sweet Apple Acres. Big. Mac built a house nearby the farm for themselves for privacy and so Sweet Apple Acres wouldn’t be too crowded.
 
Applejack and Caramel  
The parents of Golden Delicious (Del). They live on Sweet Apple Acres in Ponyville.
 
Apple Bloom and Pipsqueak  
The parents of Api Apple. They also live off the farm. However, Apple Bloom still helps out on the farm and when. Pip goes on his travels, she stays at the farm along with Api.
 
Fleur de Lis and Fancy Pants  
The parents of Crme de la Crme. They live in Canterlot.
 

 
Next Gen From Left to Right (general bios coming soon):
 

 
Anthea(Annie)
 
 
Pixel Bit (Pixie)
 
 
Turquoise Blitz (T)
 
 
Crystal Clarity (Claire)
 
 
Illusion
 
 
Nidra
 
 
Starburst (Star)
 
 
Night Light (Nighty)
 
 
Valiant Heart (Val/Lance)
 
 
Cotton Candy (CeeCee)
 
 
Cloudy Skies (Sky)
 
 
Sugar Rush
 
 
Echo
 
 
Whirlwind
 
 
Prism Bolt (Priz)
 
 
Icy Storm
 
 
Red June
 
 
Golden Delicious (Del)
 
 
Api Apple
 
 
Crme de la Crme