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精索靜脈曲張的成因至今不明;但長時間站立,經常持續增加腹腔內的壓力都有可能引致病況。 Patreon - https://www.patreon.com/darkstylerz 然而,病症的原理與陰囊內的靜脈瓣膜有關。 https://discord.gg/eTcTTqT .
 
正常的靜脈瓣膜能阻止血液倒流,由於患者陰囊內血管的缺乏瓣膜或者瓣膜失去功效,導致血液於陰囊內的靜脈積聚,並引致靜脈血管曲張、擴大,甚至在站立時於陰囊皮下浮現出來: https://discord.gg/pHkH2Tx

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